Berlin in 1945 and the Third Reich, that Hitler boasted would last a thousand years, is beginning to crumble. A German scientist makes a drastic decision that could have dire consequences for the future of humanity. South Africa in the 1970s, during the worst years of apartheid, and an appalling medical experiment, previously abandoned by its creator, is resumed. New York today, a group of eminent scientists has disappeared without a trace. Detective Michael Lorrey is forced to leave his hideaway retreat and face an unscrupulous and terrible secret organization that will stop at nothing to achieve their objective

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